關於「Aminoacyl tRNA synthetase proofreading」標籤，搜尋引擎有相關的訊息討論：

Aminoacyl-tRNA synthetases - NCBI。

Synthetases help to ensure accurate translation of the genetic code by using both highly accurate cognate substrate recognition and stringent proofreading of ...： tw | tw。

Editing of errors in selection of amino acids for protein synthesis.。

Because of this, cellular levels of aminoacyl-tRNA synthetases, as well as amino ... A proofreading function for the 3' leads to 5' exonuclease activity in ...： tw | tw。

A continuous assay for monitoring the synthetic and proofreading ...。

Aminoacyl-tRNA synthetases (aaRSs) catalyze the aminoacylation of tRNAs to produce the aminoacyl-tRNAs (aa-tRNAs) required by ribosomes for translation of ...。

Naturally Occurring Isoleucyl-tRNA Synthetase without tRNA ...。

Isoleucyl-tRNA synthetase (IleRS) is unusual among aminoacyl-tRNA synthetases in ... to the distant editing site positions the amino acid for proofreading.： tw | tw。

Engineering posttranslational proofreading to discriminate ... - PNAS。

2018年1月16日 · However, the aminoacyl-tRNA synthetases crucial for this process are polyspecific in regard to nsAAs and standard amino acids. Here, we develop ...。

A new mechanism for the hydrolytic editing function of aminoacylâ。

which aminoacyl-tRNA synthetases catalyze amino- acyl-tRNA formation. The high specificity of these ... (ii) Chemical or hydrolytic proofreading [6] postu-.。

Structural Basis for Double-Sieve Discrimination of L-Valine from L ...。

Igloi G.L.; von der Haar F. Cramer F. Hydrolytic action of aminoacyl-tRNA synthetases from baker's yeast. “Chemical proofreading” of Thr- ...。

Structural dynamics of the aminoacylation and proofreading ... - Nature。

2012年6月10日 · LeuRS is a large, multidomain, class Ia aminoacyl-tRNA synthetase (aaRS) whose essential function in all organisms is to synthesize ...。

Alanyl-tRNA Synthetase Quality Control Prevents Global ...。

2019年12月17日 · These results demonstrate the essential role of aminoacyl-tRNA proofreading in optimizing cellular fitness and suggest that any potentially ...。

Editing activity for eliminating mischarged tRNAs is essential in ...。

2017年12月8日 · These results indicate that tRNA proofreading is essential in mammalian ... It is mediated by the aminoacyl-tRNA synthetases (ARSs) that ...